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CAS Polyclonal Antibody

CAS Polyclonal Antibody

Cat no: ABP50845

Supplier: Abbkine Scientific Co.Ltd.
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Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein(chromosome segregation 1 like)may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for CSE1L.
Catalogue number: ABP50845
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunofluorescence, Immunohistochemistry - fixed, Immunoprecipitation, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: P55060
Gene: 1434
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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