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Carbonic Anhydrase IX (CA9) (APC)

Cat no: C1105-80


Supplier: United States Biological
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Carbonic anhydrase (CA) catalyzes the reversible reaction of CO2 + H2O = HCO3- + H+ , which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. CA9, also known as membrane antigen MN and renal cell carcinoma (RCC)-associated antigen G250, is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow cytometry: 10ul labels 1x10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Catalogue number: C1105-80
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.5% BSA, 0.09% sodium azide. Labeled with Labeled with Allophycocyanin (APC).
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein A/G affinity chromatography.
Additional info: Recognizes human Carbonic Anhydrase IX (CA9). Does not crossreact with recombinant mouse CA9 or with recombinant human CA1, 2, 3, 4, 5A, 6, 7, 8, 10, 12, 13 or 14.

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