A potent (Ki=0.6nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an IC50 of 0.1uM.
Solubility:
DMSO (200mg/ml) or EtOH (200mg/ml)
Molecular Weight:
~384.24
Catalogue number:
B2572-02A
Size:
1mg
Form:
Supplied as a white to off-white solid.
Purity:
~99% (HPLC)
References:
1. Ling, Y., et al. (2003). Clin.Cancer Res. 9, 1145-1154. 2. Adams, J. (2002). The Oncologist 7, 9-16.