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Nucleic Acid Delivery

Nucleic Acid Delivery
Looking for reliable and cost effective Nucleic Acid Delivery products for your research?

Nucleic acids are large molecules with strong negative charges, making it difficult or impossible for them to navigate pores in cell and nuclear membranes. In order to introduce nucleic acids, such as RNA, DNA, proteins and antibodies into cells for clinical testing and research, as well as to safely and effectively apply genetic therapies in vivo, many strategies for transfection of nucleic acids to target locations have been developed.

Synthetic nucleic acid molecules, such as small interfering RNA (siRNA), can suppress the production of disease-related proteins, for example in tumors. To operate in vivo, siRNA needs protection from nucleases, as well as from the body’s other natural protection systems. Delivery methods must consider half-life in the blood-stream, tissue specificity, toxicity and efficiency. Some proposed methods include topical delivery of gold nanoparticle-nucleic acid conjugates through the skin, and encapsulating nucleic acid molecules within liposomes. These can travel safely through the bloodstream, to be taken into a tumor or infected cell by fusing with the cell membrane, and then depositing the molecules inside the cell.

Other nucleic acid delivery methods for clinical testing and research include magnetic-assisted transfection, viral transduction, plasmid DNA injection to mouse livers, electrotransfer, endocytocis (absorption) of cationic polymers, and calcium phosphate uptake.

Reagents and kits for nucleic acid delivery include a nanoparticle transfection reagent kit; a plasmid DNA transfection reagent; custom oligonucleotide synthesis; mycoplasma removal agent; cell culture media; growth containers; and DNA, RNA and protein extraction and purification kits.

Equipment for nucleic acid delivery includes real-time PCR systems; sample coolers; thermal cyclers; tissue homogenizers, centrifuges; hybridization incubators; microplate readers; and a nucleic acid purification instrument.

Browse the product range below or simply use the Search Tool above to help find the best products.

Once you have found a product, complete a ‘Get a Quote’ form and you will get the best price!

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Universal Magnet Plate for Magnet Assisted Transfection
Universal Magnet Plate for Magnet Assisted Transfection
IBA GmbH

Universal Magnet Plate 8x13 cm suitable for Magnet Assisted Transfection (MATra) of cells grown in culture plates of different formats, e.g. 6well, 12well,...

MATra-S Immobilizer for Magent Assisted Transfection
MATra-S Immobilizer for Magent Assisted Transfection
IBA GmbH

Reagent required for Magnet Assisted Transfection of suspension cells: Suspension cells have to be made adherent first by incubating them with the reagent...

MATra-si Reagent for Magnet Assisted Transfection
MATra-si Reagent for Magnet Assisted Transfection
IBA GmbH

MATra-si Reagent for efficient transfection of siRNA/miRNA as well as Antisense Oligos (ODN) using IBA's Magnet Assisted Transfection technology (MATra)....

MATra-A Reagent for Magnet Assisted Transfection
MATra-A Reagent for Magnet Assisted Transfection
IBA GmbH

MATra-A Reagent for efficient transfection of plasmid DNA using IBA's Magnet Assisted Transfection technology (MATra). MATra is a very gentle,...

MATra-si Web Shop Starter Set (for Magnet Assisted Transfection)
MATra-si Web Shop Starter Set (for Magnet Assisted Transfection)
IBA GmbH

MATra-si Reagent for efficient transfection of siRNA/miRNA as well as Antisense Oligos (ODN) using IBA's Magnet Assisted Transfection technology (MATra)....

Air LiHa Air Displacement Pipetting Arm
Air LiHa Air Displacement Pipetting Arm
Tecan Trading AG

The Air LiHa from Tecan uses air displacement technology to provide rapid, high quality pipetting for Freedom EVO 100, 150 or 200 platforms. It can be freely...

BlockICE Sample Cooler
BlockICE Sample Cooler
Bibby Scientific

The new Techne cooling block, the BL°CKICE is ideal for incubating samples at sub-ambient temperatures. Holding two standard aluminium blocks from the...

NoICE
NoICE
Bibby Scientific

NoICE electronic ice bucketThe new N°ICE is ideal for incubating any number or size of samples at subambient temperatures for long periods of time....

Hybridiser Hybridisation Incubator
Hybridiser Hybridisation Incubator
Bibby Scientific

Hybridiser Hybridisation IncubatorHybrigene• Temperature range from 10°C above ambient to 80°C• Can hold up to 16 mini or 4 large glass...

Hybrigene Hybridisation Incubator
Hybrigene Hybridisation Incubator
Bibby Scientific

Hybrigene Hybridisation IncubatorHybrigene• Temperature range from 10°C above ambient to 80°C• Can hold up to 16 mini or 4 large glass...

PrimeQ
PrimeQ
Bibby Scientific

PrimeQ real-time PCR machineThe PrimeQ real-time PCR system has been designed with an open architecture and chemistry format that allows user flexibility in...

TC-PLUS Satellite
TC-PLUS Satellite
Bibby Scientific

TC-PLUS Advanced satellite thermal cycler (384-well)TC-Plus Thermal CyclersThe TC-PLUS thermal cyclers have all the latest features from a colour touchscreen...

TC-PLUS Satellite
TC-PLUS Satellite
Bibby Scientific

TC-PLUS Advanced satellite thermal cycler (60x0.5ml)TC-Plus Thermal CyclersThe TC-PLUS thermal cyclers have all the latest features from a colour touchscreen...

TC-PLUS Satellite
TC-PLUS Satellite
Bibby Scientific

TC-PLUS Advanced satellite thermal cycler (96x0.2ml)TC-Plus Thermal CyclersThe TC-PLUS thermal cyclers have all the latest features from a colour touchscreen...

TC-PLUS Server
TC-PLUS Server
Bibby Scientific

TC-PLUS Advanced gradient thermal cycler (384-well)TC-Plus Thermal CyclersThe TC-PLUS thermal cyclers have all the latest features from a colour touchscreen...

TC-PLUS Server
TC-PLUS Server
Bibby Scientific

TC-PLUS Advanced gradient thermal cycler (60x0.5ml)TC-Plus Thermal CyclersThe TC-PLUS thermal cyclers have all the latest features from a colour touchscreen...

TC-PLUS Server
TC-PLUS Server
Bibby Scientific

TC-PLUS Advanced gradient thermal cycler (96x0.2ml)TC-Plus Thermal CyclersThe TC-PLUS thermal cyclers have all the latest features from a colour touchscreen...

Prime gradient upgrade
Prime gradient upgrade
Bibby Scientific

Prime gradient upgrade (Prime to PrimeG)This full sized thermal cycler delivers both high performance and high throughput to provide maximum flexibility when...

PrimeG
PrimeG
Bibby Scientific

Prime thermal cycler (gradient model 384-well)This full sized thermal cycler delivers both high performance and high throughput to provide maximum...

PrimeG
PrimeG
Bibby Scientific

Prime thermal cycler (gradient model 60x0.5ml)This full sized thermal cycler delivers both high performance and high throughput to provide maximum...

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