Home  >  Products  >  Syndecan 4 (Syndecan 4 (Amphiglycan, Ryudocan), Syndecan-4, Syndecan Proteoglycan 4, SDC4, SYND4, Amphiglycan, Ryudocan Core Protein, MGC22217, OTTHUMP00000031788, Ryudocan Amphiglycan, Ryudocan)
Syndecan 4 (Syndecan 4 (Amphiglycan, Ryudocan), Syndecan-4, Syndecan Proteoglycan 4, SDC4, SYND4, Amphiglycan, Ryudocan Core Protein, MGC22217, OTTHUMP00000031788, Ryudocan Amphiglycan, Ryudocan)

Syndecan 4 (Syndecan 4 (Amphiglycan, Ryudocan), Syndecan-4, Syndecan Proteoglycan 4, SDC4, SYND4, Amphiglycan, Ryudocan Core Protein, MGC22217, OTTHUMP00000031788, Ryudocan Amphiglycan, Ryudocan)

Cat no: S9111-40C

Supplier: United States Biological
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Syndecans are heparan sulfate proteoglycans (HSPGs), which are cell-surface-associated proteins. These include Syndecans. Syndecans contain a small core protein with distinct functional domains to which are linked multiple glycosaminoglycan (GAG) chains, predominantly of the heparan sulfate variety. Syndecan synthesis is highly regulated and is dependent on both cell type and developmental state. Syndecans are involved in cell adhesion, tissue morphogenesis and differentiation and regulation of cell responsiveness to soluble growth-regulatory compounds. These functions are attributed primarily to the glycan moieties. Syndecans also interact with growth factors such as fibroblast growth factor and epidermal growth factor. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilution: ELISA (Immunogen): 0.1-1ug/ml. Western Blot: 1-3ug/ml. Optimal dilutions to be determined by the researcher. Positive Controls: Human T47D, HEP-G2, NCI-H69, SCLC and JEG cells lysates. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S9111-40C
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
References: 1. Elenius, K., et al. J Cell Biol 114, 585-95, 1991. 2. Yeaman, C. et al. J Cell Biol 122, 941-50, 1993. 3. Subramanian S. V., et al. J Biol Chem 272, 14713-20, 1997. 4. Kim C. W., et al. Mol Biol Cell 5, 797-805, 1994.
Additional info: Recognizes human Syndecan 4 at ~37kD, representing the core protein, and a band of ~22kD, representing the unglycosylated form.

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