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Synaptophysin (SYP, SYPH, SypI, Major Synaptic Vesicle Protein P38, Syn p38)

Cat no: S9108-03H


Supplier: United States Biological
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Staining of normal neuroendocrine and neoplastic neuroendocrine cells in tissue sections. The antibody recognizes presynaptic vesicles of neurons of brain, spinal cord, retina neuromuscular junctions, small vesicles of adrenal medulla and pancreatic islets. The antibody can be used for the characterisation of neuroendocrine tumors. Applications: Suitable for use in Immunohistochemistry (Fr) (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Adrenal pheochromocytoma and pancreatic islet cell neoplasm Cellular Localization: Integral membrane protein. Synaptic vesicles. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S9108-03H
Reactivities: Mouse, Rat, Bovine
Hosts: Mouse
Applications: Immunohistochemistry
Size: 1.2ml
Form: Ascitic fluid with 0.1% sodium azide
P type: Mab
Isotype: IgG1
Purity: Ascites
References: This product has been used in:Wiedenmann B & Franke WW Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 41:1017-28 (1985).
Additional info: The antibody is specific for Synaptophysin. The specificity was ascertained by immunoblotting and immunohistochemistry. Species Crossreactivity: Bovine, mouse and rat.

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