Syk (Tyrosine-protein Kinase SYK, Spleen Tyrosine Kinase)

Cat no: S9100-06C

Supplier: United States Biological

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Syk is a cytoplasmic 72kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites. Applications: Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.25-0.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S9100-06C
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Immunoprecipitation, Western Blot
Size:	25ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type:	Mab
Isotype:	IgG1,k
Purity:	Purified by immunoaffinity chromatography.
References:	1. Taniguchi T, et al. 1991. J. Biol. Chem. 266:15790. 2. Toyabe SL, et al. 2001.Immunology 103:164.
Additional info:	Recognizes mouse Syk.

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Syk (Tyrosine-protein Kinase SYK, Spleen Tyrosine Kinase)

Cat no: S9100-06C

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