Home  >  Products  >  SUPT16H (FACT Complex Subunit SPT16, Facilitates Chromatin Transcription Complex Subunit SPT16, hSPT16, FACT 140kD Subunit, FACTp140, Chromatin-specific Transcription Elongation Factor 140kD Subunit, FACT140, FACTP140)
SUPT16H (FACT Complex Subunit SPT16, Facilitates Chromatin Transcription Complex Subunit SPT16, hSPT16, FACT 140kD Subunit, FACTp140, Chromatin-specific Transcription Elongation Factor 140kD Subunit, FACT140, FACTP140)

SUPT16H (FACT Complex Subunit SPT16, Facilitates Chromatin Transcription Complex Subunit SPT16, hSPT16, FACT 140kD Subunit, FACTp140, Chromatin-specific Transcription Elongation Factor 140kD Subunit, FACT140, FACTP140)

Cat no: S8091-20C

Supplier: United States Biological
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Spt16 is a 120-140kD nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT140 complex is composed of the Spt16 and the SSRP1 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. Applications: Suitable for use in Immunoprecipitation, Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S8091-20C
Reactivities: Human
Hosts: Mouse
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Size: 25ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by Protein G affinity chromatography.
References: 1. LeRoy G, et al. 1998. Science 282:1836. 2. Orphanides G, et al. 1998. Cell 92:105. 3. Orphanides G, et al. 1999. Nature 400:284.
Additional info: Recognizes human Spt16.

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