The COOH terminal end of substance P, a short polypeptide neurotransmitter that regulates the excitability of dorsal horn nociceptive neurons. It is known to have a role in several physiologic activities such as pain transmission, the vomiting reflex, salivary secretion and smooth muscle contraction.
Applications:
Suitable for use in Immunofluorescence and Immunohistochemistry (frozen and paraffin). Other applications not tested.
Recommended Dilution:
Immunohistochemistry (frozen): 1:100-1:200
Immunohistochemistry (paraffin): 1:100-1:200
Optimal dilutions to be determined by the researcher.
Hybridoma:
NS1/1-Ag 4-1 myeloma cells with spleen cells from Wistar rat.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.