Home  >  Products  >  STK36 (Serine/Threonine Kinase 36, Fused Homolog (Drosophila), DKFZp434N0223, FU, KIAA1278, fused, serine/threonine kinase 36)

STK36 (Serine/Threonine Kinase 36, Fused Homolog (Drosophila), DKFZp434N0223, FU, KIAA1278, fused, serine/threonine kinase 36)

Cat no: S7973-59C

Supplier: United States Biological
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Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7973-59C
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as liquid 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
References: 1. Maloveryan A, Finta C, Osterlund T, Kogerman P. A possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulation. Journal of Cell Communication and Signaling 2007 Dec 1 (3-4): 165-73.
Additional info: Recognizes STK36. Sequence homology: human, canine.

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