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STAT 6 (Signal Transducer And Activator of Transcription 6, IL-4 Stat)

Cat no: S7972-42K

Supplier: United States Biological
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STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT6 is rapidly activated in response to IL-4, however the fate of the activated form is not clear. Applications: Suitable for use in Immunofluorescence, Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 5ug/ml Western Blot: 0.25-0.5ug/ml Immunocytochemistry: 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7972-42K
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Bluyssen HA and Levy DE. J Biol Chem 272: 4600-4605 (1997). 2. Darnell JE Jr. Science 277:1630-1635 (1997). 3. Quelle FW, et al. Mol Cell Biol 15(6): 3336-43. (1995). 4. Ryan P., et al. J. Biol. Chem. published July 16, 2002. 5. Leonard WJ, et al. Annu Rev Immunol 16:293-322 (1998). 6. Schindler C, et al. Annu Rev Biochem 64:621-51 (1995).
Additional info: Recognizes human STAT6. Species Crossreactivity: mouse and rat.

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