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SIGLEC8 (Sialic Acid Binding Ig-like Lectin 8, MGC59785, SAF2, SIGLEC-8, SIGLEC8L)

Cat no: S1013-61

Supplier: United States Biological
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Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:32,000. Western Blot: 0.3-1ug/ml. A band is detected at ~45kD band observed in lysates of cell line MOLT4 (calculated MW of 54kD according to NP_055257.2). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can Peptide Blocking: Corresponding peptide is available for Peptide Blocking studies. See S1013-61-P. Antibody
Catalogue number: S1013-61
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Purity: Purified by affinity chromatography.
Alternative names: SIGLEC8; sialic acid binding Ig-like lectin 8; MGC59785; SAF2; SIGLEC-8; SIGLEC8L
References: Yokoi H, Choi OH, Hubbard W, Lee HS, Canning BJ, Lee HH, Ryu SD, von Gunten S, Bickel CA, Hudson SA, Macglashan DW Jr, Bochner BS. Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement. J Allergy Clin Immunol. 2008 Feb;121(2):499-505.e1. Epub 2007 Nov 26.
Additional info: Recognizes human SIGLEC8.

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