Home  >  Products  >  Shh-a, ID (Sonic Hedgehog Protein A, SHHA, VHH-1, shh)

Shh-a, ID (Sonic Hedgehog Protein A, SHHA, VHH-1, shh)

Cat no: S1012-99M

Supplier: United States Biological
0 reviews | Write a Review Pencil
Sonic hedgehog a (shha) is a member of the hedgehog gene family. The hedgehog family of genes specifies the fate of a large number of different cell types within invertebrate and vertebrate embryos. Genetic analyses of the zebrafish orthologue of mammalian scube-2 indicates its involvement in hedgehog (Hh) signaling. Duplication events have occurred evolutionarily in teleost fish with regard to sonic hedgehog and indian hedgehog. Formation of the adenohypophysis in zebrafish is largely dependent on shha, as in mice, demonstrating highly conserved function. Hedgehog is essential to adult hematopoietic stem cell formation in zebrafish. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1012-99M
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Hollway, GE et al (2006) Dev. Biol. 294(1):104-118. 2. Ingham, PW and Kim, HR (2005) Exp. Cell Res. 306(2):336-342. 3. Herzog, W et al (2003) Dev. Biol. 254(1):36-49. 4. Gering, M and Patient, R. (2005) Dev. Cell 8(3):389-400.
Additional info: Recognizes zebrafish Shha.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave