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SFRP2, CT (Secreted Frizzled-related Protein 2, FRP-2, SARP1, SDF-5, Secreted Apoptosis Related Protein 1)

SFRP2, CT (Secreted Frizzled-related Protein 2, FRP-2, SARP1, SDF-5, Secreted Apoptosis Related Protein 1)

Cat no: S1012-87T

Supplier: United States Biological
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sFRP2, otherwise known as SARP-1 (secreted apoptosis-related protein 1), is a member of the secreted frizzled-related protein family which interact directly with Wnt, to act as soluble modulators of Wnt signalling. Several studies have linked the epigenetic silencing of the sFRP2 gene with cancer, including breast cancer, colorectal cancer, gastric cancer, renal cell carcinoma and acute myeloid leukemia. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S1012-87T
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes an epitope within the C-terminal (CT) region of human sFRP2 at ~38kD in duodenum cell lysates. Species sequence homology: mouse, rat, canine.

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