HOXC4, CT (HOXC4, HOX3E, Homeobox protein Hox-C4, Homeobox protein CP19, Homeobox protein Hox-3E)

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

036719

Size

200ul

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Park, S.R., et al. Nat. Immunol. 10(5):540-550(2009)\nLamesch, P., et al. Genomics 89(3):307-315(2007)\nWissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)\nGong, L.G., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22(5):497-501(2005)\nKim, E.C., et al. J. Biol. Chem. 279(40):42258-42269(2004)

Additional Info

Human

Alternative Names

HOXC4, HOX3E, Homeobox protein Hox-C4, Homeobox protein CP19, Homeobox protein Hox-3E