Home  >  Products  >  EAT2A/EAT2B (Sh2d1b, SH2 domain protein 1B [Mus musculus], MGI:1349420, EAT-2, EAT-2A, Eat2, Eat2a, EWS/FLI1 activated transcript 2, Sh2d1b, SH2 domain protein 1B2, EAT-2B, Eat2b, Sh2d1c, EAT-2-related transducer)
EAT2A/EAT2B (Sh2d1b, SH2 domain protein 1B [Mus musculus], MGI:1349420, EAT-2, EAT-2A, Eat2, Eat2a, EWS/FLI1 activated transcript 2, Sh2d1b, SH2 domain protein 1B2, EAT-2B, Eat2b, Sh2d1c, EAT-2-related transducer)

EAT2A/EAT2B (Sh2d1b, SH2 domain protein 1B [Mus musculus], MGI:1349420, EAT-2, EAT-2A, Eat2, Eat2a, EWS/FLI1 activated transcript 2, Sh2d1b, SH2 domain protein 1B2, EAT-2B, Eat2b, Sh2d1c, EAT-2-related transducer)

Cat no: S1012-98B

Supplier: United States Biological
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By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM] Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1012-98B
Reactivities: Mouse
Hosts: Goat
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
References: 1. Roncagalli R, Taylor JE, Zhang S, Shi X, Chen R, Cruz-Munoz ME, Yin L, Latour S, Veillette A. Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Nat Immunol. 2005 Oct;6(10):1002-10. PMID: 16127454.
Additional info: Recognizes EAT2A/EAT2B. Sequence Homology: mouse.

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