Yes-associated protein (YAP) was identified based on its ability to associate with the SH3 domain of Yes. It also binds to other SH3 domain containing proteins such as Nck, Crk, Src, and Abl. YAP is a transcriptional coactivator. It interacts with 13-3-3 and suppresses apoptosis.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.