Home  >  Products  >  XPC (Xeroderma Pigmentosum Complementation Group C, Xeroderma Pigmentosum Group C Complementing Protein, Xeroderma Pigmentosum Group C Protein, XP C, XP-C, XP Group C, XPC Gene, XPCC, DNA Repair Protein Complementing XP C Cells, DNA Repair Protein Complem

XPC (Xeroderma Pigmentosum Complementation Group C, Xeroderma Pigmentosum Group C Complementing Protein, Xeroderma Pigmentosum Group C Protein, XP C, XP-C, XP Group C, XPC Gene, XPCC, DNA Repair Protein Complementing XP C Cells, DNA Repair Protein Complem

Cat no: X1045-70


Supplier: United States Biological
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Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair. Applications: Suitable for use in Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Raji whole cell lysate Cellular Localization: Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: X1045-70
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: PBS [pH7.2]
P type: Mab
Isotype: IgG
Purity: As reported
References: 1. de Laat WL et al. Molecular mechanism of nucleotide excision repair. Genes Dev, 13: 768-85, (1999). PUBMED:10197977 2. Aboussekhra A et al. Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 80: 859-68, (1995). PUBMED:7697716
Additional info: Recognizes human XPC.

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