Home  >  Products  >  VDAC1 (Voltage-dependent Anion-selective Channel Protein 1, VDAC-1, hVDAC1, Outer Mitochondrial Membrane Protein Porin 1, Plasmalemmal Porin, Porin 31HL, Porin 31HM, VDAC)
VDAC1 (Voltage-dependent Anion-selective Channel Protein 1, VDAC-1, hVDAC1, Outer Mitochondrial Membrane Protein Porin 1, Plasmalemmal Porin, Porin 31HL, Porin 31HM, VDAC)

VDAC1 (Voltage-dependent Anion-selective Channel Protein 1, VDAC-1, hVDAC1, Outer Mitochondrial Membrane Protein Porin 1, Plasmalemmal Porin, Porin 31HL, Porin 31HM, VDAC)

Cat no: V2121-20J

Supplier: United States Biological
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The Voltage-Dependent Anion Channel (VDAC or mitochondrial Porin)I is an outer membrane mitochondrial protein. The VDAC protein is thought to form the major pores through which adenine nucleotides are transferred through the outer mitochondrial membrane. VDAC has also been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, ANT, and CypD is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2121-20J
Reactivities: Human, Mouse, Rat, Bovine, Porcine, Rabbit
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human VDAC/Porin at ~31kD. Species Crossreactivity: mouse, rat, bovine, porcine and rabbit.

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