Home  >  Products  >  Vascular Endothelial Growth Factor Receptor 1 (VEGF Receptor 1, VEGFR 1, VEGFR1, VEGFR-1, EC 2.7.10.1, FLT, Fms-like Tyrosine Kinase 1, Flt 1, Flt1, Flt-1, Fms Related Tyrosine Kinase 1, Fms-related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Va

Vascular Endothelial Growth Factor Receptor 1 (VEGF Receptor 1, VEGFR 1, VEGFR1, VEGFR-1, EC 2.7.10.1, FLT, Fms-like Tyrosine Kinase 1, Flt 1, Flt1, Flt-1, Fms Related Tyrosine Kinase 1, Fms-related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Va

Cat no: V2110-16M


Supplier: United States Biological
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VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: ELISA: 1.5-8ug/ml Immunoprecipitation: 1-5ug/ml Western Blot: 1-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: V2110-16M
Reactivities: Human, Mouse
Hosts: Mouse
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Reconstitute with 100ul sterile ddH2O.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography
References: 1. Malgorzata M. et al. Positive Feedback between Vascular Endothelial Growth Factor-A Autotaxin in Ovarian Cancer Cells. Mol. Cancer Res. March 2008; 6(3).
Additional info: Recognizes native and denaturated human VEGFR-1/ Flt-1 in ELISA experiments and on the surface of different human cell types. SpeciesCcrossreactivity: mouse

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