Home  >  Products  >  TrkC (Tyrosine Kinase Receptor C, Trk C, Trk-C Tyrosine Kinase, EC 2.7.10.1, ETS-related Protein Neurotrophic Receptor Tyrosine Kinase Fusion, ETV6 NTRK3 Fusion, GP145 TrkC, gp145(TrkC), GP145-TrkC, Neurotrophic Tyrosine Kinase Receptor Type 3, NTRK 3, NT

TrkC (Tyrosine Kinase Receptor C, Trk C, Trk-C Tyrosine Kinase, EC 2.7.10.1, ETS-related Protein Neurotrophic Receptor Tyrosine Kinase Fusion, ETV6 NTRK3 Fusion, GP145 TrkC, gp145(TrkC), GP145-TrkC, Neurotrophic Tyrosine Kinase Receptor Type 3, NTRK 3, NT

Cat no: T8663-23A


Supplier: United States Biological
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The Trk family of tyrosine protein kinase receptors is responsible for mediating the trophic effects of the NGF family of neurotrophins. TrkC is mainly expressed in nervous tissue and is a functional receptor for neurotrophin 3 (NT3). Although it is primarily expressed in neural lineages, expression can also be detected in some non neural cells. Four forms of TrkC are produced by alternative splicing. Isoform A is full length TrkC. Isoform B differs from A between amino acids 529 to 612 and is missing amino acids 613 to 839. Isoform C of TrkC is missing amino acids 712 to 725. Isoform D is missing amino acids 402 to 410. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:100-1000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T8663-23A
Reactivities: Mouse
Hosts: Rat
Applications: Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder in PBS. Reconstitute in 500ul 40-50% glycerol, PBS.
P type: Mab
Isotype: IgG1
Purity: Purified
Additional info: Recognizes mouse TrkC. Does not react with mouse TrkB.

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