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TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor) (PE)

Cat no: T8282-09B


Supplier: United States Biological
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TREM-1 stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock. Clone has been shown to activate monocytes and granulocytes. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat 20ul labels 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Recommended Negative Controls: Mouse IgG1 Negative Control (PE) Mouse IgG1 Negative Control (PE) Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: T8282-09B
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25Tests
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 0.2% BSA.
P type: Mab
Isotype: IgG1
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes triggering receptor expressed on myeloid cells 1 (TREM-1), a receptor expressed on CD14+ monocytes, macrophages and neutrophils. It is also highly expressed in inflammatory lesions caused by fungi and bacteria.

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