Transforming Growth Factor Beta (TGF-beta) is a stable, multifunctional polypeptide growth factor. While specific receptors for this protein have been found on almost all mammalian cell types thus far examined, the effect of the molecule varies depending on the cell type and growth conditions. Generally, TGF-beta is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. It is now known that the originally described form of TGF-beta, now described as TGF-beta1, is only one of a family of regulatory proteins consisting of a number of proteins distantly related to TGF-beta1 (30-40% sequence homology) and a number of more closely related proteins (70-80% sequence homology) designated TGF-beta2, TGF-beta1.2, TGF-beta3, TGF-beta4, and TGF-beta5.
Suitable for use in Flow Cytometry. Other applications not tested.
Flow Cytometry: 10ul labels 1x10e6 cells
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Stable for 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.