Home  >  Products  >  TRAIL (TNF-related Apoptosis-inducing Ligand, Apo-2 Ligand, APO2L, Apo-2L, CD253, Protein TRAIL, TL2, Tumor Necrosis Factor Ligand Superfamily Member 10, TNFSF10)
TRAIL (TNF-related Apoptosis-inducing Ligand, Apo-2 Ligand, APO2L, Apo-2L, CD253, Protein TRAIL, TL2, Tumor Necrosis Factor Ligand Superfamily Member 10, TNFSF10)

TRAIL (TNF-related Apoptosis-inducing Ligand, Apo-2 Ligand, APO2L, Apo-2L, CD253, Protein TRAIL, TL2, Tumor Necrosis Factor Ligand Superfamily Member 10, TNFSF10)

Cat no: T8180-06C

Supplier: United States Biological
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TRAIL (TNF-related apoptosis-inducing ligand), a member of the TNF ligand family, is a type II membrane protein and expressed in a variety of human tissues. Two death domains containing receptors DR4 and DR5 have been identified as the receptors for TRAIL and two decoy receptors designated DcR1 and DcR2 inhibit TRAIL function. The multiple receptors suggest a complex role for regulation of signaling by the cytokine. TRAIL induces apoptosis and NF-kB activation in many tissues and cells. Applications: Suitable for use in ELISA, Western Blot and Neutralization. Other applications not tested. Recommended Dilution: ELISA: 2-3ug/ml Western Blot: 0.5-1ug/ml Neutralization: 5-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8180-06C
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human TRAIL.

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