Home  >  Products  >  Thyroid Stimulating Hormone (TSH, Thyroid-stimulating Hormone alpha Chain, TSH alpha, TSH A, TSHA, Thyroid-stimulating Hormone beta, Thyroid-stimulating Hormone beta Subunit, Thyroid-stimulating Hormone Subunit beta, TSH beta, TSH B, TSHB, TSH-B, Anterior
Thyroid Stimulating Hormone (TSH, Thyroid-stimulating Hormone alpha Chain, TSH alpha, TSH A, TSHA, Thyroid-stimulating Hormone beta, Thyroid-stimulating Hormone beta Subunit, Thyroid-stimulating Hormone Subunit beta, TSH beta, TSH B, TSHB, TSH-B, Anterior

Thyroid Stimulating Hormone (TSH, Thyroid-stimulating Hormone alpha Chain, TSH alpha, TSH A, TSHA, Thyroid-stimulating Hormone beta, Thyroid-stimulating Hormone beta Subunit, Thyroid-stimulating Hormone Subunit beta, TSH beta, TSH B, TSHB, TSH-B, Anterior

Cat no: T5400-43A

Supplier: United States Biological
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Thyroid-stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T5400-43A
Reactivities: Human
Hosts: Mouse
Applications: ELISA
Size: 1mg
Form: Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes the whole molecule of human Thyroid Stimulating Hormone (TSH). Does not crossreact with human LH, FSH or HCG.

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