SUC1 is a CDK subunit from S. pombe that interacts with CDK1. SUC1 is used exclusively to capture CDK1 complexes from various cell lines and egg extracts. SUC1 belongs to the CKS family. It binds to the catalytic subunit of the cyclin dependent kinase (cdc2) and is essential for its biological function. SUC1 forms a homodimer (in presence of zinc).
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Cellular Localization: Cytoplasmic and Nuclear.
Storage and Stability:
May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.