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SSEA-4 (SSEA-4, Stage-Specific Embryonic Antigen-4, Stage Specific Embryonic Antigen 4, SSEA4)

SSEA-4 (SSEA-4, Stage-Specific Embryonic Antigen-4, Stage Specific Embryonic Antigen 4, SSEA4)

Cat no: S6610-10J

Supplier: United States Biological
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This antibody reacts with the Stage-specific embryonic antigen-4 (SSEA-4) that is expressed upon the surface of human teratocarcinoma stem cells (EC), human embryonic germ (EG) cells) and human embryonic stem (ES) cells. No immunoreactivity is evident with undifferentiated murine EC, ES and EG cells. Expression of SSEA-4 is down-regulated following differentiation of human EC cells. In contrast, the differentiation of murine EC and ES cells may be accompanied by an increase in SSEA-4 expression. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S6610-10J
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 25ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Mab
Isotype: IgG3,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Kannagi, R., et al., EMBO J. 2: 2355 (1983). 2. Gang E.J. et al. Blood. Feb 15;109(4):1743-51 (2007). 3. Henderson, J.K., et al. Stem Cells. 20: 329 (2002). 4. Mu?ller T, et al. Hum Reprod. 2009 Feb 27 (2009).
Additional info: Recognizes human SSEA-4.

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