Home  >  Products  >  SB-431542 (4-[4-(1,3-Benzodioxol-5-yl)-5-Pyridin-2-yl-1H-Imidz-ol-2-yl]Benzamide)

SB-431542 (4-[4-(1,3-Benzodioxol-5-yl)-5-Pyridin-2-yl-1H-Imidz-ol-2-yl]Benzamide)

Cat no: S0098-93A


Supplier: United States Biological
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A potent and selective inhibitor of the TGF-b1 receptor ALK5 (IC50 = 94nM). It inhibits ALK4 only at higher concentrations (IC50 = 140nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway. Molecular Weight: ~384.39 Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S0098-93A
Size: 1mg
Form: Supplied as a liquid in DMSO.
Purity: ~98% (HPLC)

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