Home  >  Products  >  RSK2, NT (Ribosomal S6 Kinase 2, RSK-2, p90-RSK2, pp90RSK2, 90kD Ribosomal Protein S6 Kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated Protein Kinase 1, ISPK1, ISPK-1, MAP Kinase-activated Protein Kinase 1b, MAPK-activated Protein Kinase 1b, MAPKAP Kinase
RSK2, NT (Ribosomal S6 Kinase 2, RSK-2, p90-RSK2, pp90RSK2, 90kD Ribosomal Protein S6 Kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated Protein Kinase 1, ISPK1, ISPK-1, MAP Kinase-activated Protein Kinase 1b, MAPK-activated Protein Kinase 1b, MAPKAP Kinase

RSK2, NT (Ribosomal S6 Kinase 2, RSK-2, p90-RSK2, pp90RSK2, 90kD Ribosomal Protein S6 Kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated Protein Kinase 1, ISPK1, ISPK-1, MAP Kinase-activated Protein Kinase 1b, MAPK-activated Protein Kinase 1b, MAPKAP Kinase

Cat no: R9400-01E

Supplier: United States Biological
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RSK2 is a member of the family of 90-kD ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK2 phosphorylates a wide range of substrates, including ribosomal protein S6, and plays a significant role in mediating extracellular signal-related kinase (ERK) signal transduction. Mutations in RSK2 have been found to be associated with Coffin-Lowry syndrome (3). Applications: Suitable for use in Flow Cytometry, Western Blotting, Immunoprecipitation, Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50 Western Blotting: 1:5,000 (90kD) Immunohistochemistry: 1:250 Immunoprecipitation: 1:100 1ug/mg of total cell protein (~10e7 cells) Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: R9400-01E
Reactivities: Human
Hosts: Rabbit
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid.
P type: Mab
Isotype: IgG
Purity: Supernatant
Alternative names: Ribosomal Protein S6 Kinase 90kDa Polypeptide 3, CLS, EC=2.7.11.1, HU-3, MRX19, RSK
References: 1. Moller, D.E., et al. Human rsk isoforms: cloning and characterization of tissue-specific expression. Am J Physiol. 266(2 Pt 1): C351
Additional info: Recognizes human RSK2.

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