Purified anti-EGFR Phosphorylated (Tyr1068)

Cat no: 656302

Supplier: BioLegend

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Description
Additional Information

EGFR is a transmembrane glycoprotein that belongs to protein kinase superfamily. It is expressed in tissues of epithelial, mesenchymal and neuronal origin and plays major roles in proliferation, differentiation and development. Binding of the protein to its ligand induces receptor dimerization and tyrosine autophosphorylation. Mutations or over-expression of this gene are associated with certain forms of cancer. Tyrosine 1068 is the primary autophosphorylation site in the C-terminal domain of the receptor.

Catalogue number:	656302
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	200 microl
Clone:	Poly6563
Gene:	1956
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5-10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at -20C.
Antigen:	KLH conjugated modified synthetic peptide
Isotype:	Rabbit Polyclonal IgG
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Epidermal growth factor receptor, HER1