Home  >  Products  >  Prostate Specific Membrane Antigen (PSMA, PSM, Folate Hydrolase, FOLH, FGCP, Glutamate Carboxypeptidase 2, GCP2, Membrane Glutamate Carboxypeptidase, mGCP, N-acetylated alpha-linked Acidic Dipeptidase 1, NAALAD1, NAALADase I, NAALAdase, Pteroylpoly gamma

Prostate Specific Membrane Antigen (PSMA, PSM, Folate Hydrolase, FOLH, FGCP, Glutamate Carboxypeptidase 2, GCP2, Membrane Glutamate Carboxypeptidase, mGCP, N-acetylated alpha-linked Acidic Dipeptidase 1, NAALAD1, NAALADase I, NAALAdase, Pteroylpoly gamma

Cat no: P9054-63N


Supplier: United States Biological
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PSMA (prostate specific membrane antigen) is a 100-120kD type II, integral membrane glycoprotein,1 composed of a 19 amino acid intracellular domain containing the N-terminus, a 24 amino acid transmembrane region, and a 707 amino acid extracellular C-terminal domain. The PSMA gene has been cloned and sequenced, and has been localized to chromosome 11q. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. Applications: Suitable for use in ELISA, Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Immunofluorescence: 1:200-1:300 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P9054-63N
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunofluorescence, Western Blot
Size: 50ul
Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Rajasekaran SA, et al., (2008) Mol Cancer Ther 7(7):2142-2151 2. Polly D.G, et al., (2005) Int J Cancer 116(3):415-421 3. Susan F.S, et al., (2005) Expert Opin Ther Targets 9(3):561-570
Additional info: Recognizes human PSMA.

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