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PPARG (Peroxisome Proliferator-activated Receptor gamma, PPAR-gamma, Nuclear Receptor Subfamily 1 Group C Member 3, NR1C3)

PPARG (Peroxisome Proliferator-activated Receptor gamma, PPAR-gamma, Nuclear Receptor Subfamily 1 Group C Member 3, NR1C3)

Cat no: P5505-06K

Supplier: United States Biological
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PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARg is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism, PPARg also modulates insulin sensitivity, cell proliferation and inflammation. The inhibition of PPARg transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARg. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P5505-06K
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes ~33kD band, corresponding to human PPARg (isoform CRA-c). Species Crossreactivity: mouse.

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