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PBR (BZRP, Translocator Protein, Peripheral-type Benzodiazepine Receptor, PKBS, Mitochondrial Benzodiazepine Receptor, MBR, TSPO)

PBR (BZRP, Translocator Protein, Peripheral-type Benzodiazepine Receptor, PKBS, Mitochondrial Benzodiazepine Receptor, MBR, TSPO)

Cat no: P3344-60D

Supplier: United States Biological
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PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18kD) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34kD voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Immunohistochemistry (Frozen and paraffin): 10-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P3344-60D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes mouse PBR. Species Crossreactivity: human and rat.

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