Opioid receptors are a group of G protein coupled receptors which are used by the class of substances known as opioids. The aa sequence of the three opioid receptor subtypes bears ~70% homology and they have ~40% homology with somatostatin receptor SSTR1. The delta opioid receptor (delta-opioid receptor or DOR) has enkephalins as its endogenous ligands. It is distributed in various parts of the CNS as well as in some smooth muscles. It is known to mediate analgesia. These receptors have been shown to interact with beta-2 adrenergic receptors, arrestin beta 1 and GPRASP1. Delta opioid receptor agonists are considered to be potential anti-depressants.
Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Western Blot: 1-20ug/ml
Immunohistochemistry: 40-150ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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