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Products Nod2
| Catalogue number: | N3006-02 |
| Reactivities: | Human |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Form: | Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide before the addition of glycerol to 40% |
| P type: | Mab |
| Isotype: | IgG1,k |
| Purity: | Purified by immunoaffinity chromatography. |
| References: | 1. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB: J. Bertin, et al.; J. Biol. Chem. 274, 12955 (1999) 2. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB: N. Inohara, et al. ; J. Biol. Chem. 274, 14560 (1999) 3. An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways : N. Inohara, et al. ; J. Biol. Chem. 275, 27823 (2000) 4. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB: Y. Ogura, et al.; J. Biol. Chem. 276, 4812 (2001) 5. Induction of Nod2 in myelomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation: O. Gutierrez, et al. ; J. Biol. Chem. 277, 41701 (2001) 6. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease: Y. Ogura, et al. ; Nature 411, 603 (2001) 7. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease: J.P. Hugot, et al. ; Nature 411, 599 (2001) 8. Human Nod1 confers responsiveness to bacterial lipopolysaccharides : N. Inohara, et al. ; J. Biol. Chem. 276, 2551 (2001) 9. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis: Y. Ogura, et al. ; Gut 52, 1591 (2003) |
| Additional info: | Recognizes human Nod2 at 116kD.. |
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