Home  >  Products  >  NK1.1 Cell Surface Antigen (Killer Cell Lectin-like Receptor Subfamily B Member 1C, CD161 Antigen-like Family Member C, Lymphocyte Antigen 55c, Ly-55c, NKR-P1.9, NKR-P1C, Natural Killer Cell Surface Protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c)

NK1.1 Cell Surface Antigen (Killer Cell Lectin-like Receptor Subfamily B Member 1C, CD161 Antigen-like Family Member C, Lymphocyte Antigen 55c, Ly-55c, NKR-P1.9, NKR-P1C, Natural Killer Cell Surface Protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c)

Cat no: N2851-75F


Supplier: United States Biological
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NK1.1, a member of the NKR-PI family of cell surface receptors, is a type II integral membrane protein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129).1-4 NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells.5-7 Applications:
Catalogue number: N2851-75F
Reactivities: Mouse
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation
Conjugates: Biotin
Size: 500ug
Form: Supplied as a liquid in PBS, 0.1% sodium azide. Conjugated to Biotin.
P type: Mab
Isotype: IgG2a,k
Purity: Purified
References: 1. Koo, G., and J. Peppard. 1984. Hybridoma 3:301-303. 2. Yokoyama, W.M., and W.E. Seaman, 1993. Ann. Rev. Immunol. 11:613-635. 3. Yu, Y.Y.L., V. Kumar, and M. Bennett. 1992. Ann. Rev. Immunol. 10:189-213. 4. Vicari, A. P., and Zlotnik, A. 1996. Immunol. Today 17:71-76. 5. Karlhofer, F.M., and W.M. Yokoyama. 1991. J. Immunol. 146:3662-3673. 6. Koo, G. C., F. J. Dumont, M. Tutt, J. Hackett,Jr., and V. Kumar. 1986. J. Immunol. 137:3742. 7. Lanier, L.L. 1997. Immunity 6:371-378. 8. Sentman, C.L., J. Hackett, Jr., T.A. Moore, M.M. Tutt, M. Bennett, and V. Kumar. 1989. Hybridoma 8:605-614.
Additional info: Recognizes mouse NK1.1 alloantigen, Mr 80-85kD (39kD under reducing conditions).

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