Home  >  Products  >  Necrostatin-7 ((Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7)
Necrostatin-7 ((Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7)

Necrostatin-7 ((Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7)

Cat no: N2059-27

Supplier: United States Biological
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A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway. Molecular Weight: ~371.41 Solubility: DMSO or EtOH Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO or EtOH. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: N2059-27
Size: 5mg
Form: Supplied as a yellow solid.
Purity: ~98% (NMR)
Alternative names: (Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7
References: 1. Zheng, W., et al. (2008). Bioorg. Med. Chem. 18, 4932-4935.

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