Home  >  Products  >  NCoR2 (Nuclear Receptor Co-repressor 2, Nuclear Receptor Corepressor 2, N-CoR2, CTG Repeat Protein 26, CTG26, Silencing Mediator for Retanoid and Thyroid Hormone Receptors, SMAP270, SMRT, SMRTE, SMRTE tau, T3 Receptor-associating Factor, Thyroid Retinoic

NCoR2 (Nuclear Receptor Co-repressor 2, Nuclear Receptor Corepressor 2, N-CoR2, CTG Repeat Protein 26, CTG26, Silencing Mediator for Retanoid and Thyroid Hormone Receptors, SMAP270, SMRT, SMRTE, SMRTE tau, T3 Receptor-associating Factor, Thyroid Retinoic

Cat no: N0555-05E


Supplier: United States Biological
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Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: HBL100 Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: N0555-05E
Reactivities: Human
Hosts: Mouse
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: No buffer.
P type: Mab
Isotype: IgG1,k
Purity: Ascites
References: 1.Chen, D.J. and Evans, R.M. (1995) A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377: 454-457
Additional info: Specific for human SMRT.

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