Home  >  Products  >  NCAM-L1 (APC) (L1CAM, L1 cell adhesion molecule CAML1, CD171, HSAS, HSAS1, MASA, MIC5, Neural cell adhesion molecule L1, S10, SPG1)

NCAM-L1 (APC) (L1CAM, L1 cell adhesion molecule CAML1, CD171, HSAS, HSAS1, MASA, MIC5, Neural cell adhesion molecule L1, S10, SPG1)

Cat no: N0547


Supplier: United States Biological
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The Neural Cell Adhesion Molecule L1 (NCAM-L1/CD171), also called L1-CAM or L1, is an Immunoglobulin superfamily (IgSF) adhesion molecule critical for neural development. NCAM-L1 binds homophilically and heterophilically with adhesion molecules including Axonin-1, CD9, Neurocan, and Integrins. Mutations of the gene encoding NCAM-L1 are associated with a subset of X-linked mental retardation syndromes, schizophrenia, and other neurological disorders. Cancer cells can proteolytically cleave NCAM-L1, releasing the soluble ectodomain. Within the ECD, human NCAM-L1 shares 86% and 87% aa identity with mouse and rat NCAM-L1, respectively. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
Catalogue number: N0547
Reactivities: Mouse
Hosts: Rat
Applications: Immunocytochemistry
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.5% BSA and 0.1% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes mouse NCAM-L1.

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