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MTA2 (Metastasis-associated Protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 Protein, p53 Target Protein in Deacetylase Complex, MTA1L1, PID)

MTA2 (Metastasis-associated Protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 Protein, p53 Target Protein in Deacetylase Complex, MTA1L1, PID)

Cat no: M3884-42L

Supplier: United States Biological
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PID/MTA2, also termed MTA1-L1, is a novel molecule that has been found to be involved in p53 pathway. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylastion of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: M3884-42L
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human MTA2 at ~75kD. Does not react with MTA1. Species Crossreactivity: mouse and rat.

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