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MHC Class 2 (beta chain) (PE)

Cat no: M3887-55D

Supplier: United States Biological
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Human MHC Class II (HLA-DP, DQ & DR) molecules are expressed on dendritic cells, monocytes, macrophages, and myeloid cells. MHC Class II molecules are heterodimers of polymorphic transmembrane a- and b-chains and generally bind exogenously derived peptides of about 10-17 amino acids. MHC Class II molecules interact with the T cell receptor on CD4+T cells. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: M3887-55D
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Western Blot
Size: 120Tests
Form: Supplied as a liquid in 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. T.A. de Kretser, et al, (1982) Eur J Immunol 12: 214-221. 2. R. Busch & J.B. Rothbard, (1990) 3. J Immunol Methods 134: 1-22. K.W. Wacherpfennig & J.L. Strominger, (1995) J Exp Med 181:161-168.
Additional info: Recognizes a monomorphic class II beta chain epitope.

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