Home  >  Products  >  MDM2 (Murine Double Minute-2, Double Minute 2 Protein, HDM2, HGNC:6973, Mdm2 Transformed 3T3 Cell Double Minute 2, p53 Binding Protein (Mouse) Binding Protein 104kD, MDM2BP, MGC71221, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, Oncopro

MDM2 (Murine Double Minute-2, Double Minute 2 Protein, HDM2, HGNC:6973, Mdm2 Transformed 3T3 Cell Double Minute 2, p53 Binding Protein (Mouse) Binding Protein 104kD, MDM2BP, MGC71221, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, Oncopro

Cat no: M2800-09A


Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Cellular Localization: Nuclear and cytoplasmic. Expressed predominantly in the nucleoplasm. Interaction with ARF (P14) results in the localisation of both proteins to the nucleus. The nucleolar localisation signals in both ARF and MDM2 may be necessary to allow efficient nucleolar localisation of both proteins. Positive Control: Breast carcinoma. Applications: Suitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: M2800-09A
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry
Size: 50ul
Form: 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
P type: Mab
Isotype: IgG1,k
Purity: Purified by Protein G affinity chromatography.
References: Hickman ES et al. Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. Oncogene 9:2177-81 (1994). Picksley SM et al. Immunochemical analysis of the interaction of p53 with MDM2;--fine mapping of the MDM2 binding site on p53 using synthetic peptides. Oncogene 9:2523-9 (1994).
Additional info: Species Crossreactivity: Crossreacts with Human, Rat and Mouse. Not yet tested in other species.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave