Home  >  Products  >  MCSP (Melanoma-associated Chondroitin Sulfate Proteoglycan, Chondroitin Sulfate Proteoglycan 4 (Melanoma Associated), Chondroitin Sulfate Proteoglycan 4, Chondroitin Sulfate Proteoglycan NG2, CSPG4, MCSPG, MEL-CSPG, Melanoma Chondroitin Sulfate Proteoglyc
MCSP (Melanoma-associated Chondroitin Sulfate Proteoglycan, Chondroitin Sulfate Proteoglycan 4 (Melanoma Associated), Chondroitin Sulfate Proteoglycan 4, Chondroitin Sulfate Proteoglycan NG2, CSPG4, MCSPG, MEL-CSPG, Melanoma Chondroitin Sulfate Proteoglyc

MCSP (Melanoma-associated Chondroitin Sulfate Proteoglycan, Chondroitin Sulfate Proteoglycan 4 (Melanoma Associated), Chondroitin Sulfate Proteoglycan 4, Chondroitin Sulfate Proteoglycan NG2, CSPG4, MCSPG, MEL-CSPG, Melanoma Chondroitin Sulfate Proteoglyc

Cat no: M2755-25

Supplier: United States Biological
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Proteoglycans (PGs) are a family of proteins composed of different polypeptide chains containing glycosaminoglycan (GAG) modifications. They vary in their cellular locations and have diverse structure and functions. MCSP is a proteoglycan found in the nervous system, comprising a large integral membrane PG with a core protein of 300kD and at least one covalently attached chondroitin sulfate (CS) GAG chain. In the CNS this protein is expressed mainly on the surfaces of developing and adult oligodendrocyte precursor cells, but is also associated with developing chondrocytes, cardiomyocytes, pericytes and several human tumors. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:10-1:1000 Western Blot: 1:1000 Immunofluorescence (IC): 1:100 Immunoprecipitation: 1:10-1:100 Immunohistochemistry(Paraffin/frozen): 1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: M2755-25
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tri-glycine, 150mM sodium chloride, 0.05% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Kinney HC, Haynes RL, Xu G, Andiman SE, Folkerth RD, Sleeper LA, Volpe JJ. Neuron deficit in the white matter and subplate in periventricular leukomalacia. Ann Neurol;71(3):397-406. 2012 Mar. (ICC, IF, Human).
Additional info: Recognizes human MCSP at ~300kD.

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