Home  >  Products  >  MBD4 (Methyl-CpG-binding Domain Protein 4, Methyl-CpG-binding Endonuclease 1, Methyl-CpG-binding Protein MBD4, Mismatch-specific DNA N-glycosylase, MED1)
MBD4 (Methyl-CpG-binding Domain Protein 4, Methyl-CpG-binding Endonuclease 1, Methyl-CpG-binding Protein MBD4, Mismatch-specific DNA N-glycosylase, MED1)

MBD4 (Methyl-CpG-binding Domain Protein 4, Methyl-CpG-binding Endonuclease 1, Methyl-CpG-binding Protein MBD4, Mismatch-specific DNA N-glycosylase, MED1)

Cat no: M2480-02

Supplier: United States Biological
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MBD4 (methyl-CpG-binding domain protein 4) belongs to the MBD family of nuclear proteins that bind to methylated CpG sites and represses gene transcription. Human proteins MECP2, MBD1, MBD2, and MBD4, except MBD3 bind specifically to methylated DNA. MBD4 exhibits thymine glycosylase activity and is known to play an important function in DNA mismatch repair and apoptosis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: M2480-02
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes mouse MBD4. Species Crossreactivity: human and rat.

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