Catalogue number: |
M2352-20F |
Reactivities: |
Human, Mouse, Rat, Bovine, Drosophila/Arthropod, Non-Human Primate, Porcine, Zebrafish/Fish |
Hosts: |
Rabbit |
Applications: |
Flow Cytometry |
Size: |
500ul |
Form: |
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, 50% glycerol, 0.02% sodium azide. |
P type: |
Mab |
Isotype: |
IgG |
Purity: |
Purified |
References: |
Roux, P.P. and Blenis, J. (2004) Microbiol Mol Biol Rev 68, 320-44.Baccarini, M. (2005) FEBS Lett 579, 3271-7.Meloche, S. and Pouyssegur, J. (2007) Oncogene 26, 3227-39.Roberts, P.J. and Der, C.J. (2007) Oncogene 26, 3291-310.Rubinfeld, H. and Seger, R. (2005) Mol Biotechnol 31, 151-74.Murphy, L.O. and Blenis, J. (2006) Trends Biochem Sci 31, 268-75.Dalby, K.N. et al. (1998) J Biol Chem 273, 1496-505.Marais, R. et al. (1993) Cell 73, 381-93.Kortenjann, M. et al. (1994) Mol Cell Biol 14, 4815-24.Owens, D.M. and Keyse, S.M. (2007) Oncogene 26, 3203-13. |
Additional info: |
Recognizes endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when either dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), or singly phosphorylated at Thr202. Does not cross-react with the corresponding phosphorylated residues of either JNK/SAPK or p38 MAP kinases. Species crossreactivity: human, mouse, rat, monkey, porcine, hamster, bovine, D.melanogaster and zebrafish. |