Lysine-specific demethylase 1(LSD1) is also known as AOF2, is a nuclear amine oxidase. LSD1 contain a Swirm domain, a FAD-binding motif and an amine oxidase domain that can act as a histone demethylase as well as transcription cofactor. LSD1 activity is inhibited by the amine oxidase inhibitors pargyline, deprenyl, clorgyline and tranylcypromine.
Suitable for use in Western Blot. Other applications not tested.
Western Blot: 2-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.