Home  >  Products  >  Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L

Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L

Cat no: L2640-11A


Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
PAFAH alpha encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. It is expressed ubiquitously in both the frontal and occipital areas of the brain. Defects in PAFAH alpha cause lissencephaly type 1 (LIS1) and of subcortical band heterotopia (SBH). Defects in PAFAH alpha are also a cause of Miller-Dieker lissencephaly syndrome (MLDS). Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degrees C. Aliquot and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: L2640-11A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
P type: Mab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human Lissencephaly-1.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave