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LDLR (Low-density Lipoprotein Receptor, LDL Receptor)

Cat no: L2601-03G


Supplier: United States Biological
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Low density lipoprotein receptors (LDLR) are cell surface glycoproteins that regulate LDL cholesterol by scavenging LDL from the blood. LDLR is characterized by a cluster of cysteine-rich class A repeats, EGF-like repeats, the O-linked sugars domain and six YWTD or class B repeats. Mutations in the LDLR gene cause autosomal dominant disease such as familial hypercholesterolemia (FH) and atherosclerosis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: L2601-03G
Reactivities: Human, Mouse, Rat, Bovine, Rabbit
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes mature human LDLR (~160kD), LDLR precursor (~120kD) and LDLR monomer (~50kD). Species Crossreactivity: mouse, rat, hamster, rabbit and bovine.

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