Home  >  Products  >  Lat2 (Linker for Activation of T-cells Family Member 2, Linker for Activation of B-cells, Non-T-cell Activation Linker, Lab, Ntal, Wbscr5)
Lat2 (Linker for Activation of T-cells Family Member 2, Linker for Activation of B-cells, Non-T-cell Activation Linker, Lab, Ntal, Wbscr5)

Lat2 (Linker for Activation of T-cells Family Member 2, Linker for Activation of B-cells, Non-T-cell Activation Linker, Lab, Ntal, Wbscr5)

Cat no: L1390-08

Supplier: United States Biological
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Non-T cell Activation Linker (NTAL) is also known as linker for activation of B cells (LAB), is a transmembrane adaptor protein. NTAL is expressed in B cells, mast cells, monocytes and NK cells. When NTAL is tyrosine phosphorylated, it recruits signalling molecules such as Grb2, Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome, a rare genetic disorder. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: L1390-08
Reactivities: Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes rat NTAL/LAB at ~22kD.

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