KCNIP3 (Calsenilin, A-type Potassium Channel Modulatory Protein 3, DRE-antagonist Modulator, DREAM, Kv Channel-interacting Protein 3, KChIP3, CSEN, DREAM)

Cat no: D9450-01C

Supplier: United States Biological

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Calsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2, a protein involved in Alzheimer's disease, to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function, is a substrate for caspase-3, acts as a calcium regulated transcriptional suppressor, and interacts with A-type potassium channels. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2-6ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	D9450-01C
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.1% BSA, 0.01% thimerosal, 30% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by Protein A affinity chromatography.
Additional info:	Recognizes human Calsenilin at ~30kD. Species Crossreactivity: mouse and rat.

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KCNIP3 (Calsenilin, A-type Potassium Channel Modulatory Protein 3, DRE-antagonist Modulator, DREAM, Kv Channel-interacting Protein 3, KChIP3, CSEN, DREAM)

Cat no: D9450-01C

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